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Overview

This animation, by MScBMC student Felix Son, explores the dynamic changes in the actin cytoskeleton that work in concert to enable cell motility:

  • Actin cytoskeleton assembly with a discussion of 3 phases: nucleation, elongation, and steady state, and their role in the assembly of actin filaments

  • Structure of filopodia and lamellipodia,

  • Role of protrusion, adhesion, and contraction in cell movement

Suggested Use

Biology instructors can use this animation to help undergraduate students understand the complex dynamics associated with actin assembly and cell motility.

The Role of Actin in Cell Motility

Dynamic changes in the actin cytoskeleton allow for cell motility

Animation: The role of actin in cell motility



The animation was originally created for use in undergraduate biology at UC Davis. The interactions between the visualization designer and team members throughout the development process were recorded and analysed by Kevin Wee. As well, Wee evaluated the efficacy of the visualization at various points during production with undergraduate students at Purdue University.

Latest projects

Contributors

Felix Son

Felix Donghwi Son

Jodie Jenkinson

Jodie Jenkinson

Marc Dryer

Marc Dryer

Susan Keen

Susan Keen

Gaël McGill

Gaël McGill

Materials

Animation: The role of actin in cell motility (Vimeo)

Funding

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